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Deliverability Letter

421 4.7.0

421 4.7.0 Temporary System Problem

Temporary Failure

Exchange Online is temporarily unavailable. Retry the delivery later.

421 4.7.0 usually reflects a transient Microsoft service interruption. Respect the retry interval or Microsoft may extend the deferral.

Severity

WARNING

Provider

Microsoft 365 / Outlook

Reference

Mitigation Portal

Last Reviewed

2025-06-01

How to Fix 421 4.7.0

Follow these steps to resolve this Microsoft 365 / Outlook SMTP error and restore normal delivery.

  • Implement exponential backoff when retrying the message.
  • Monitor the Microsoft 365 Service Health dashboard for incidents.
  • Spread retries across multiple connectors to avoid overwhelming a single region.
  • Document the timeline in case recipients open a support ticket.

Still experiencing Microsoft 365 / Outlook delivery issues?

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